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7,8-didehydro-4,5α-epoxy-17-methylmorphinan- 3,6α,10α-triol (10S-hydroxymorphine), fluorine-to-carbon ratios (FC) can easily be calculated based on the integrated intensity of the various components of the C1 s spectrum by the following equation: F143ICF3 þ2ICF2 þICF ð6:1Þ C IC1s where C1 s is the total area under the C1 s signal and C1x is the peak area of each fluorinated group .
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